July 30, 2020, Vancouver, Canada – iCo Therapeutics Inc. (TSXV: ICO) (OTCQB: ICOTF) (“iCo” or “the Company”) and its subsidiary, iCo Therapeutics Australia Pty Ltd., announced today the publication of results of their Oral Amphotericin B (iCo 019) Phase 1a Study in one of the leading infectious diseases journals, Antimicrobial Agents and Chemotherapy entitled “Phase I Clinical Study to evaluate the safety, tolerability, and pharmacokinetics of a novel oral amphotericin B formulation (ICO-019) in healthy human subjects”

Dr. Kishor M. Wasan, Director of Research at iCo Therapeutics Inc. and Adjunct Professor and Distinguished University Scholar in the Department of Urologic Sciences, Faculty of Medicine at the University of British Columbia is the inventor of this technology and the senior author on this paper, along with co-authors Drs Peter Hnik and Ellen Wasan.

“The publication of this paper represents an important milestone for the development of oral amphotericin B and reaffirms the scientific importance of this work” states Dr. Wasan.

The results of the Phase 1 clinical study revealed that iCo-19 has a long circulation time and systemic exposure without the gastrointestinal, liver, and kidney toxicities associated with parental administered amphotericin B products and reaffirmed the potential of iCo-19 as a new treatment strategy for a wide array of infectious diseases.

“The publication of results of our phase 1 clinical study precedes initiation of our phase 2 efficacy studies in the near future” stated Chief Medical Officer and First Author, Dr Peter Hnik.

Details of this publication can be found at:
https://aac.asm.org/content/early/2020/07/15/AAC.01450-20

About iCo Therapeutics

iCo Therapeutics identifies existing development stage assets for use in underserved ocular and infectious diseases. Such assets may exhibit utility in non-ophthalmic conditions outside the Company’s core focus areas and if so the Company will seek to capture further value via partnerships. iCo shares trade on the TSX Venture Exchange under the symbol “ICO” and on the OTCQB under the symbol “ICOTF”.

For more information, visit the Company website at: icotherapeutics.cdmail.biz.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward-Looking Statements

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Contact:

Investor Relations
iCo Therapeutics Inc.
1-604-800-9860