News Releases - icotherapeutics.com http://icotherapeutics.com/newsroom/ News Releases Sun, 17 Dec 2017 22:44:52 en 251 iCo Therapeutics Announces Third Quarter 2017 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQB: ICOTF), today reported financial results for the quarter ended September 30, 2017. http://icotherapeutics.com/_resources/news/nr_20171128.pdf 2017-11-28 11:48:00 250 iCo Therapeutics Announces Ethics Approval for its Oral Amphotericin B Phase 1 Clinical Study http://icotherapeutics.com/_resources/news/nr_20171122.pdf 2017-11-22 00:00:00 246 iCo Therapeutics Announces Upcoming Presentations and Meetings http://icotherapeutics.com/_resources/news/nr_20170907.pdf 2017-09-07 00:00:00 249 iCo Therapeutics Announces Second Quarter 2017 Financial Results http://icotherapeutics.com/_resources/news/nr_20170829.pdf 2017-08-29 00:00:00 248 iCo Therapeutics Inc. Approves Advance Notice Policy http://icotherapeutics.com/_resources/news/nr_20170804.pdf 2017-08-04 00:00:00 247 iCo Therapeutics Announces Election of Directors http://icotherapeutics.com/_resources/news/nr_20170630.pdf 2017-06-30 00:00:00 245 iCo Therapeutics Announces Pre IND meeting for Novel Glaucoma Asset iCo Therapeutics (TSXV: ICO) (OTCQB: ICOTF) ("iCo" or "the Company"), today reported it will hold a pre IND meeting with the Division of Transplantation and Ophthalmology, US Food and Drug Administration (FDA) on June 21st, 2017. http://icotherapeutics.com/_resources/news/nr_June_15_2017.pdf 2017-06-15 00:00:00 244 iCo Therapeutics Announces Positive Oral Amphotericin Study iCo Therapeutics (TSXV: ICO) (OTCQB: ICOTF) ("iCo" or "the Company"), today reported the successful conclusion of pre-clinical studies involving its lead oral Amphotericin B candidate, including compelling safety data http://icotherapeutics.com/_resources/news/nr_June_12_2017.pdf 2017-06-12 00:00:00 243 iCo Therapeutics Announces First Quarter 2017 Financial Results iCo Therapeutics (TSXV: ICO) (OTCQB: ICOTF) ("iCo" or "the Company"), today reported financial results for the quarter ended March 31, 2017. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financi http://icotherapeutics.com/_resources/news/nr_May_24_2017.pdf 2017-05-24 00:00:00 240 iCo Therapeutics Announces Year End 2016 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQB: ICOTF), today reported financial results for the year ended December 31, 2016. http://icotherapeutics.com/_resources/news/nr_Apr_19_2017.pdf 2017-04-19 00:00:00 242 iCo Therapeutics Inc. Announces No Material Change iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX‐V: ICO) (OTCQB: ICOTF) reports that at the request of IIROC, the Company wishes to confirm that management is unaware of any material change in their operations that would account for the recent increa http://icotherapeutics.com/_resources/news/nr_March_13_2017.pdf 2017-03-13 00:00:00 238 iCo Therapeutics Announces Positive Study Results and Significant Advances related to Oral Amphotericin B Program iCo Therapeutics (“iCo” or “theCompany”) (TSX-°©‐V: ICO) (OTCQX: ICOTF) announces several developments related to its novel, patent protected formulation of generic Amphotericin B: http://icotherapeutics.com/_resources/news/nr_2016_11_28.pdf 2016-11-28 00:00:00 237 iCo Therapeutics Announces Third Quarter 2016 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended September 30, 2016. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Fina http://icotherapeutics.com/_resources/news/nr_2016_11_24.pdf 2016-11-24 00:00:00 236 iCo Therapeutics Announces World Wide Exclusive Option and EU License Rights with Laboratorios SALVAT for Novel Glaucoma Asset iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced a World Wide Exclusive Option and EU License Rights with Laboratorios SALVAT for a Novel Glaucoma Asset. http://icotherapeutics.com/_resources/news/nr_2016_11_15.pdf 2016-11-15 00:00:00 235 iCo Therapeutics Announces Second Quarter 2016 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX‐V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended June 30, 2016. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International F http://icotherapeutics.com/_resources/news/nr_2016_08_19.pdf 2016-08-19 00:00:00 234 iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that all nominees listed in the management information circular dated May 30, 2016 were elected as directors at its 2016 Annual Meeting of Shareholders, held on June 24 http://icotherapeutics.com/_resources/news/nr_2016_06_27.pdf 2016-06-27 00:00:00 231 iCo Therapeutics Announces Year End 2015 Financial Results April 14, 2016, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the year ended December 31, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and pr http://icotherapeutics.com/_resources/news/nr_2016_04_14.pdf 2016-04-14 00:00:00 230 iCo Therapeutics Inc. Announces Grant of Stock Options and Recent CEO Share Purchases iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announces the grant of stock options to directors, officers and consultants to the Company. http://icotherapeutics.com/_resources/news/nr_2016_02_17.pdf 2016-02-17 00:00:00 229 iCo Strategic Reorganization iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that effective immediately, in an effort to preserve its asset base and maximize shareholder value, the company is undertaking a strategic re-organization. http://icotherapeutics.com/newsroom/index.php?content_id=229 2016-01-18 00:00:00

January 18, 2016, Vancouver, Canada — iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that effective immediately, in an effort to preserve its asset base and maximize shareholder value, the company is undertaking a strategic re-organization.

“Following the announcements of negative top-line and sub-group iCo-007 data sets iCo commenced an exhaustive search for both additional life science assets to acquire as well as potential business combinations,” remarked iCo Chief Executive Officer, Andrew Rae. “To date, post a detailed review of many opportunities, we have been unable to conclude a value enhancing transaction which would have made sense for iCo and its shareholders. Management continues to believe that the current market capitalization of the Company does not accurately reflect iCo’s intrinsic value, given our current cash position of approximately $3.38 million dollars – after giving effect to all severance liabilities – plus the value of our iCo-008 and Oral Amphotericin B assets. Furthermore, raising equity capital at current share prices to enhance the value of these assets would prove to be excessively dilutive. Consequently, management is commencing a process to preserve iCo’s cash resources, continue development of existing assets and investigate non-dilutive sources of funding for iCo-008 and the Oral Drug Delivery platform, while at the same time maintain an ability to pursue new business opportunities.”

Cash preservation: steps are now being taken to significantly reduce iCo’s monthly burn rate and fixed costs, which includes the termination of all employees. Andrew Rae and John Meekison will be retained in a reduced consulting capacity to continue their CEO and CFO positions, respectively. It is also anticipated that certain key persons including Dr. Peter Hnik who has acted as Chief Medical Officer historically will also participate in a consulting capacity. Remaining non-essential expenses will be eliminated.

Enhancing value of life science assets: iCo remains very excited about our Israeli partner’s progress with regards to using Bertilimumab (iCo-008) to treat bullous pemphigoid and ulcerative colitis, and data on these Phase II trials is expected in H1 2016 and Q4 2016, respectively. Additionally, iCo maintains all rights to use Bertilimumab for eye diseases, and will continue exploring opportunities to partner this asset.

Oral Amphotericin B (“Oral AmpB”): iCo has now entered the process of manufacturing scale-up for the Oral AmpB compound in preparation for clinical trials. We are also pursuing additional avenues to fund this program both in terms of possible partnerships, potential non-dilutive funding such as grants, and/or raising capital in such a way as not to be dilutive to iCo’s equity base. Recent efforts have focused on European sources of capital and non-dilutive funds.

Continued search for new opportunities: in addition to further developing our existing assets, Management will continue to search for new business opportunities. Such a search will not be restricted to the life science area, but will include other industries which could enhance value for iCo’s shareholders.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases. iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1. With Phase 2 clinical history, Bertilimumab (iCo-008) is a candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration. iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release..

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws. Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com
Andrew Rae, CEO
iCo Therapeutics
778-772-7775
rae@icotherapeutics.com
Michael Moore, Investor Relations
NATIONAL Equicom
858-886-7813
mmoore@national.ca
]]>
228 iCo Therapeutics Announces Changes to Board of Directors iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced the appointment of Susan Koppy and John Meekison to iCo’s Board of Directors. http://icotherapeutics.com/newsroom/index.php?content_id=228 2015-12-24 00:00:00

December 24, 2015, Vancouver, Canada — iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced the appointment of Susan Koppy and John Meekison to iCo’s Board of Directors.

Ms. Koppy has more than 30 years of experience in marketing and business development in the bio-pharmaceutical industry in the U.S., Europe, and Japan.  She has participated in the negotiation of numerous agreements with a multi-billion dollar aggregate commercial value and is a frequent speaker on business development issues in the industry.  After 15 years working through progressive positions of responsibility in life sciences, Ms. Koppy joined Novartis Pharmaceuticals AG in Basel Switzerland in 2000 where she became the first woman on the global marketing management team.  Between 2005 and 2008 she built and led strategy, business development and acquisition groups for Applied Biosystems, Inc., Idenix Pharmaceuticals and Transcept Pharmaceuticals where she successfully sourced and executed a major U.S. partnership with Purdue Pharmaceuticals.  Ms. Koppy now consults with a variety of bio-pharmaceutical companies on business development strategy, search, and transactions in a broad variety of therapeutic areas both in- and out-licensing.  She is a member of the National Association for Corporate Directors, Healthcare Businesswomen’s Association, and Licensing Executive Society. 

Mr. Meekison, CPA, CMA, P.Log., CIM is a co-founder and has been CFO of iCo Therapeutics Inc. since February 2005.  He is a former investment banker having worked at a number of investment firms including:  Loewen Ondaatje McCutcheon; Haywood Securities; Dlouhy Merchant Group; and PI Financial Corp.  As a financier, Mr. Meekison has raised equity capital for technology and biotechnology companies both in Canada and the United States.  Mr. Meekison’s areas of expertise include: financial/treasury management, risk management, capital formation, corporate governance, mergers and acquisitions and business strategy.   Mr. Meekison sits on the Board of Directors of Sojourn Ventures Inc. and Natcore Technology Inc.  Mr. Meekison is a Chartered Professional Accountant, a Certified Investment Manager and Professional Logistician.  He received his BA from the University of British Columbia.

As Ms. Koppy and Mr. Meekison join the Board of Directors, Doug Janzen and Noel Hall will step down, effective immediately. Mr. Janzen and Mr. Hall are thanked by the board and management for their service.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is a candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
NATIONAL Equicom
858-886-7813
mmoore@national.ca

]]>
226 iCo Therapeutics Announces Third Quarter 2015 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended September 30, 2015. http://icotherapeutics.com/newsroom/index.php?content_id=226 2015-11-24 00:00:00

November 24, 2015, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended September 30, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”).

“As we continue to progress our oral delivery platform for Amp B we’ve also seen iCo-008 value building via our partner progressing systemic use indications, including a recently announced IND in the United States” said Andrew Rae, President & CEO of iCo Therapeutics. “These advancements regarding iCo-008 are not only value enriching for this clinical program, but also continue to give us confidence in its potential therapeutic application in ophthalmological indications.”
 
Subsequent Events to Quarter End

  • Announced manufacturing update for Amp B wherein iCo engaged Corealis Pharma Inc., a contract manufacturing organizing, for analytical development, formulation optimization and scale-up of the Amp B oral delivery system. Preparation and regulatory filings are expected to be complete in 2016, and Phase 1A study data is expected to be available in 2017.
  • Further strengthened intellectual property around the oral delivery platform for Amp B with a recent issuance of a composition of matter and use patent, bringing the total number of issued patents to eleven.  We continue to pursue additional issuances in multiple jurisdictions.

Summary Third Quarter 2015 Results
iCo incurred a total comprehensive loss of $165,386 (loss per share of $0.00) for the quarter ended September 30, 2015, compared to total comprehensive gain of $393,677 (earnings per share of $0.00) for the quarter ended September 30, 2014, representing an increased loss of $559,063.  This increase in loss is primarily a result of the change in value of our investment in Immune Pharmaceuticals Inc.

Research and development expenses were $134,093 for the quarter ended September 30, 2015 compared to $85,720 for the quarter ended September 30, 2014, representing an increase of $48,373. This increase in research and development expenses is primarily due to development activities with our Amp B program.

For the quarter ended September 30, 2015 general and administrative expenses were $253,652 compared to $328,696 for the quarter ending September 30, 2014, representing a decrease of $75,044, primarily as a result of reduced stock based compensation.

Liquidity and Outstanding Share Capital
As at September 30, 2015, we had cash and cash equivalents and short-term investments of $4,343,859. 

As at November 24, 2015, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
NATIONAL Equicom
858-886-7813
mmoore@national.ca

]]>
225 iCo Therapeutics Announces Manufacturing Update for Oral Amp B Program iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF) today announced that the company has engaged Corealis Pharma Inc. (“Corealis”) a contract manufacturing organization, for analytical development, formulation optimization and scale http://icotherapeutics.com/newsroom/index.php?content_id=225 2015-10-26 13:46:00

October 26, 2015, Vancouver, Canada – iCo Therapeutics Inc. (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF) today announced that the company has engaged Corealis Pharma Inc. (“Corealis”) a contract manufacturing organization, for analytical development, formulation optimization and scale-up of the amphotericin B oral delivery system.  The preparation and regulatory filings for this program are expected to be completed in 2016, with Phase 1A study data available in 2017.

“This is a significant step in the advancement of the oral delivery platform,” said Andrew Rae, President and CEO of iCo Therapeutics.  “This work will support manufacturing for a first-in-human phase one clinical study.”

“We are very excited to be working with Corealis on further development of Oral Amphotericin B and are optimistic in moving this technology forward to the clinic in due course,” said Dr. Kishor Wasan, Dean of the College of Pharmacy and Nutrition at the University of Saskatchewan and Adjunct Professor and Distinguished University Scholar at the University of British Columbia.

iCo has also been building its intellectual property position around the Oral Amphotericin B asset. The company was issued composition of matter and use patents and management is aggressively pursuing further patent issuances in multiple jurisdictions as it moves towards the clinic.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide ophthalmic rights to iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward-Looking Statements
Certain information contained in this news release, including any information relating to the proposed transaction (the “Transaction”) and each issuer’s future financial or operating performance may be deemed "forward-looking". These statements relate to future events or future performance and reflect each issuer’s expectations regarding the Transaction, and the future growth, results of operations, business prospects and opportunities of iCo, Diagnos and the combined company. These forward-looking statements also reflect each issuer’s current internal projections, expectations or beliefs and are based on information currently available to iCo or Diagnos, respectively. In some cases forward-looking information can be identified by terminology such as "may", "will", "should", "expect", "intend", "plan", "anticipate", "believe", "estimate", "projects", "potential", "scheduled", "forecast", "budget" or the negative of those terms or other comparable terminology. Assumptions upon which such forward looking information regarding completion of the Transaction are based include that iCo and Diagnos will be able to satisfy the conditions to the Transaction, that the required approvals will be obtained from the shareholders and optionholders of each issuer, as applicable, that all third party regulatory and governmental approvals to the Transaction will be obtained and all other conditions to completion of the Transaction will be satisfied or waived. Although iCo and Diagnos believe that the forward-looking information contained in this news release is based on reasonable assumptions, readers cannot be assured that actual results will be consistent with such statements. Accordingly, readers are cautioned against placing undue reliance on forward-looking information. iCo and Diagnos expressly disclaim any intention or obligation to update or revise any forward-looking information, whether as a result of new information, events or otherwise, except in accordance with applicable securities laws.

For Further Information, Contact:

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
NATIONAL Equicom
858-886-7813
mmoore@national.ca

 

]]>
224 iCo Therapeutics Announces Second Quarter 2015 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended June 30, 2015. http://icotherapeutics.com/newsroom/index.php?content_id=224 2015-08-26 11:35:00

August 26, 2015, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended June 30, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”).

“We continue pre-clinical activities with respect to our Oral Amp B program, rapidly advancing towards the selection of a contract manufacturer,” said Andrew Rae, President & CEO of iCo Therapeutics. “We have also seen our partner make Phase two clinical advancements with the support of a $21.5 million financing. Over the course of the fall we hope to provide updates with respect to due diligence on complimentary assets.”

Summary Second Quarter 2015 Results
iCo incurred a total comprehensive loss of $738,607 (loss per share of $0.01) for the quarter ended June 30, 2015, compared to total comprehensive loss of $2,982,109 (loss per share of $0.04) for the quarter ended June 30, 2014, representing a reduced loss of $2,243,502.  This decrease is primarily a result of the both the sale and change in value of our investment in Immune Therapeutics Inc., as well completion of our iCO-007 iDEAL trial.

Research and development expenses were $176,049 for the quarter ended June 30, 2015 compared to $401,396 for the quarter ended June 30, 2014, representing a reduction of $225,347. This decrease in research and development expenses is primarily due to the completion of the iCo-007 iDEAL trial.

For the quarter ended June 30, 2015 general and administrative expenses were $480,852 compared to $569,783 for the quarter ending June 30, 2014, representing a decrease of $88,931, primarily as a result of reduced stock based compensation.

Liquidity and Outstanding Share Capital
As at June 30, 2015, we had cash and cash equivalents and short-term investments of $4,532,017. 

As at August 28, 2015, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
NATIONAL Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
223 iCo Therapeutics Announces Voting & Election Results from Annual Meeting of Shareholders iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that all nominees listed in the management information circular dated June 1, 2015 were elected as directors at its 2015 Annual Meeting of Shareholders, held earlier to http://icotherapeutics.com/newsroom/index.php?content_id=223 2015-06-26 12:32:00 June 26, 2015, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that all nominees listed in the management information circular dated June 1, 2015 were elected as directors at its 2015 Annual Meeting of Shareholders, held earlier today, June 26 2015. On a vote by ballot, the following 5 nominees proposed by management were elected as Directors of iCo Therapeutics to serve until the Company’s next Annual Meeting of Shareholders or until their successors are elected or appointed, with shares represented at the meeting voting in favour of individual nominees as follows:

Director For % Withheld %
Andrew Rae 5,837,490 90.37 621,750 9.63
William Jarosz 5,837,490 90.37 621,750 9.63
Richard Barker 5,837,490 90.37 621,750 9.63
Noel Hall 6,415,740 99.33 43,500 0.67
Douglas Janzen 6,415,740 99.33 43,500 0.67


Please refer to the Company's management information circular available on SEDAR at www.sedar.com for more details on the matters covered at the annual meeting.  Final voting results on all matters voted on at the annual meeting will also be filed on SEDAR.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
222 iCo Therapeutics Announces First Quarter 2015 Financial Results May 28, 2015, Vancouver, Canada — iCo Therapeutics ("iCo" or "the Company") (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended March 31, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and pres http://icotherapeutics.com/newsroom/index.php?content_id=222 2015-05-28 13:13:00 May 28, 2015, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the quarter ended March 31, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”).

“The Oral Platform advancing Amp B is progressing and we are actively looking at several external programs and assets that may provide further value to iCo,” said Andrew Rae, President & CEO of iCo Therapeutics. 

Summary First Quarter 2015 Results
iCo incurred a total comprehensive loss of $252,397 (loss per share of $0.00) for the quarter ended March 31, 2015, compared to total comprehensive earnings of $1,365,068 (earnings per share of $0.02) for the quarter ended March 31, 2014, representing an increased loss of $1,617,465.  The increase is primarily a result of changes related to our holdings in Immune Pharmaceuticals, Inc.

Research and development expenses were $149,554 for the quarter ended March 31, 2015 compared to $624,891 for the quarter ended March 31, 2014, representing a reduction of $475,337. This decrease in research and development expenses is based mainly on reduced expenses associated with the wind-down of the iDEAL study.

For the quarter ended March 31, 2015 general and administrative expenses were $279,218 compared to $365,591 for the quarter ending March 31, 2014, representing a decrease of $86,373, primarily as a result of reduced stock based compensation expense.

Liquidity and Outstanding Share Capital
As at March 31, 2015, we had cash and cash equivalents and short-term investments of $6,079,783 compared to $5,707,787 as at December 31, 2014. 

As at May 28, 2015, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company holds worldwide rights to an oral drug delivery platform, with Oral Amphotericin B (Amp B) as the initial platform candidate, utilizing a known anti-fungal drug to treat life-threatening infectious diseases.  iCo also has worldwide rights to two drug candidates: iCo-007 is a second generation antisense drug candidate targeting C-Raf kinase and iCo-008 is a monoclonal antibody targeting eotaxin-1.  With Phase 2 clinical history, Bertilimumab (iCo-008) is candidate for the treatment of vernal or atopic keratoconjunctivitis and wet age-related macular degeneration.  iCo-008 is in Phase 2 clinical studies with iCo’s partner, Immune Pharmaceuticals. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
221 iCo Therapeutics Announces Year End 2014 Financial Results iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the year ended December 31, 2014. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financia http://icotherapeutics.com/newsroom/index.php?content_id=221 2015-04-27 13:07:00

April 27, 2015, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the year ended December 31, 2014. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”).

“Last year’s phase two DME results did not provide the outcome management and investors had hoped for, but extremely undervalued assets remain at iCo Therapeutics”, said Andrew Rae, President & CEO of iCo Therapeutics. “We entered 2015 with a focus on those assets and plans to drive significant value this year.  We remain committed to our oral Amphotericin B clinical study plans and continue to assess complimentary assets which the Company may consider in-licensing or acquiring.  We also look forward to additional data this year from our partner, Immune Pharma, as they recently confirmed timing and advancement of their clinical programs using iCo-008 in their yearend announcement.”

2014 Financial & Operational Highlights

  • Announced plans to complete pre-clinical studies and regulatory filings in preparation for moving Oral AmpB into an initial Phase 1A clinical trial.  The program will utilize approximately $700,000 of funding and technological advice from the National Research Council of Canada Industrial Research Assistance Program (NRC-RAP), under the Canadian HIV Technology Development (CHTD) Program.
  • Presented findings on the Company’s Oral AmpB program at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition held in San Diego.
  • Reported results of its Oral AmpB drug candidate targeting latent HIV reservoirs.  The study evaluated in vitro effectiveness of Oral AmpB in reactivating latent HIV viral reservoirs which remain present in individuals despite intensive treatment with antiretroviral therapy.
  • Completed overnight marketed equity offering of 16,206,483 units for aggregate gross proceeds of $6.75 million.
  • Received approval from the Depository Trust Company for its United States trading symbol ICOTF, providing the Company with DTC eligibility.
  • Announced the winding down of Phase 2 diabetic macular edema (“DME”) activities related to iCo-007.   

Summary Fiscal 2014 Results
iCo incurred a total comprehensive loss of $2,079,657 for the year ended December 31, 2014 compared to a total loss of $5,918,965 for the year ended 2013, representing a decrease of $3,839,308. The decrease in our net and comprehensive loss was principally caused by a reduction of clinical trial costs associated with the iDEAL study.

Research and development expenses were $669,485 for the year ended December 31, 2014 compared to $4,075,840 for the year ended December 31, 2013, representing a decrease of $3,406,355. This decrease in research and development expenses is based mainly on the wind down of clinical costs associated with the iDEAL study.

For the year ended December 31, 2014 general and administrative expenses were $1,590,444 compared to $2,061,405 for the year ending December 31, 2013, representing a decrease of $470,961, principally due to a reduction in stock based compensation expense for employees, directors and consultants.

Liquidity and Outstanding Share Capital
As at December 31, 2014, we had cash and cash equivalents and short-term investments of $5,707,787 compared to $1,903,389 as at December 31, 2013.  The company also closed a unit offering on January 27, 2014, for gross proceeds of $6,750,000.

As at April 27, 2015, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company has exclusive worldwide rights to two drug candidates - iCo-007 for Diabetic Macular Edema (DME) and iCo-008 for other sight-threatening diseases. iCo-007 is in Phase 2 clinical studies for DME. With Phase 2 clinical history, Bertilimumab (iCo-008) is targeted for the treatment of keratoconjunctivitis and wet age-related macular degeneration. In addition, iCo holds worldwide rights to an oral drug delivery platform. The first platform candidate is the Oral Amp B Delivery system, utilizing a known anti-fungal drug to treat life-threatening infectious diseases. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
217 iCo Therapeutics Announces Third Quarter 2014 Financial Results and Corporate Update iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the nine months ended September 30, 2014. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International http://icotherapeutics.com/newsroom/index.php?content_id=217 2014-11-28 13:12:18 November 28, 2014, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the nine months ended September 30, 2014.  Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”). 

Management also announced that it has wound down its Phase 2 diabetic macular edema (“DME”) activities related to iCo-007.  iCo will continue to investigate  other potential use indications for its licensed technology, which targets the C-Raf kinase pathway. 

“The Phase 2 iCo-007 DME data that has been presented,  along with our internal analysis,  has not demonstrated any subgroup response rates that warrant further financial investment by iCo in the DME program at this time,” said Andrew Rae, President & CEO of iCo Therapeutics.  “Since day one at iCo, we have been focused on redefining existing drug candidates for new or expanded use indications. We continue with that same model as we prepare for an oral Amphotericin B (“Oral AmpB”) clinical study, while concurrently investigating the ability to expand our proprietary oral delivery platform and  assessing complimentary assets which the Company may consider in-licensing or acquiring.”

Management continues to anticipate additional Bertilimumab (iCo-008) Phase 2 clinical data related to ulcerative colitis and bullous pemphigoid, based on the guidance provided by its NASDAQ-listed partner Immune Pharmaceuticals. iCo currently owns 654,486 shares and 123,649 warrants of Immune Pharmaceuticals [NASDAQ: IMNP] and the opportunity to earn up to  $32M in milestone payments as its partner progresses through clinical milestones.

Third Quarter 2014 Highlights

  • Reported results of its Oral AmpB drug candidate targeting latent HIV reservoirs.  The study evaluated in vitro effectiveness of Oral AmpB in reactivating latent HIV viral reservoirs which remain present in individuals despite intensive treatment with antiretroviral therapy.

Subsequent Events to Quarter End

  • Announced plans to complete pre-clinical studies and regulatory filings in preparation for moving Oral AmpB into an initial Phase 1A clinical trial.  The program will utilize approximately $700,000 of funding and technological advice from the National Research Council of Canada Industrial Research Assistance Program (NRC-RAP), under the Canadian HIV Technology Development (CHTD) Program.
  • Presented findings on the Company’s Oral AmpB program at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition held in San Diego.

Summary Third Quarter 2014 Results
iCo incurred total comprehensive loss of $1,223,363 (loss per share of $0.02) for the nine months ended September 30, 2014 compared to a total comprehensive loss of $5,220,617 (loss per share of $0.07) for the nine months ended September 30, 2013, representing a decrease of $3,997,254 in comprehensive loss.  The decrease in net comprehensive loss is primarily a result of an increase in the carrying value of our investment in Immune Pharmaceuticals, as well as a decrease in expenses associated with the iDEAL trial.

Research and development expenses were $1,112,007 for the nine months ended September 30, 2014 compared to $3,558,167 for the nine months ended September 30, 2013, representing a reduction of $2,446,160. This decrease in research and development expenses is based mainly on reduced expenses associated with the iDEAL study.

For the nine months ended September 30, 2014 general and administrative expenses were $1,264,070 compared to $1,589,172 for the nine months ending September 30, 2013, representing a decrease of $325,102, primarily as a result of reduced stock based compensation expense and professional fees.

Liquidity and Outstanding Share Capital
As at September 30, 2014, we had cash and cash equivalents and short-term investments of $5,729,313. 

As at November 28, 2014, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company has exclusive worldwide rights to two drug candidates - iCo-007 for Diabetic Macular Edema (DME) and iCo-008 for other sight-threatening diseases. iCo-007 is in Phase 2 clinical studies for DME. With Phase 2 clinical history, Bertilimumab (iCo-008) is targeted for the treatment of keratoconjunctivitis and wet age-related macular degeneration. In addition, iCo holds worldwide rights to an oral drug delivery platform. The first platform candidate is the Oral Amp B Delivery system, utilizing a known anti-fungal drug to treat life-threatening infectious diseases. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
216 iCo Therapeutics Announces Oral Amphotericin Presentations at AAPS iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that presentations regarding the company’s Oral Amphotericin B drug candidate will be made at the American Association of Pharmaceutical Scientists (AAPS) Annual Meetin http://icotherapeutics.com/newsroom/index.php?content_id=216 2014-11-04 04:01:00 November 4, 2014, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced that presentations regarding the company’s Oral Amphotericin B drug candidate will be made at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition. The event takes place at the San Diego Convention Center November 2 – 6.

Dr. Kishor M. Wasan, Professor and Dean, College of Pharmacy and Nutrition at the University of Saskatchewan, will present the following:

  • Poster on November 4 between 9:30 and 12:30: T2099 - Novel Oral Amphotericin B Formulation Remains Highly Effective against Murine Systemic Candidiasis following Exposure to Tropical Temperature
  • Panel Moderation on November 5 from 9:00 – 11:00: Antimicrobials, Super BUGS and Global Health
  • Presentation on November 5 from 2:25 to 2:50: Development of a Tropically Stable Oral Lipid Formulation of Amphotericin B for the Treatment of Systemic Fungal Infections and Visceral Leishmaniasis

Dr. Kishor Wasan, along with Dr. Ellen Wasan, Assistant Professor, College of Pharmacy and Nutrition, University of Saskatchewan, invented the delivery technology at the University of British Columbia in 2008.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company has exclusive worldwide rights to iCo-007 and iCo-008, as well as an oral drug delivery platform. The first platform candidate being tested is the Oral Amp B Delivery system, utilizing a known anti-fungal drug to treat latent HIV reservoirs, parasitic and life-threatening infectious diseases. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws.  Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com
Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com
]]>
215 iCo Therapeutics Announces Advancement of Oral Amphotericin B Program iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced next steps for its Oral Amphotericin B program. http://icotherapeutics.com/newsroom/index.php?content_id=215 2014-10-22 04:01:00 October 22, 2014, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today announced next steps for its Oral Amphotericin B program. The company recently announced positive findings from its in vitro work involving samples from HIV/AIDS patients exposed to HAART therapy. iCo now plans to complete pre clinical studies and regulatory filings to move forward with an initial Phase 1A clinical trial, utilizing approximately $700,000 of funding and technological advice from the National Research Council of Canada Industrial Research Assistance Program (NRC-IRAP), under the Canadian HIV Technology Development (CHTD) Program.

“Advancing the Oral Amphotericin B program follows the company’s long standing business plan to advance currently approved therapeutics by employing reformulation and delivery technologies for new or expanded use indications,” said Andrew Rae, President & CEO of iCo Therapeutics.  “There is a growing interest in addressing the issue of flushing latent HIV reservoirs, in addition to life threatening fungal and parasitic infections which may be impacted by a novel and more accessible formulation of Amphotericin B. Numerous parties are now attempting to repurpose drugs for such purposes and Oral Amphotericin B represents one such approach. We are excited to complete pre-clinical toxicology studies and initiate Phase 1A work in human subjects. We are thankful for the support from NRC-IRAP CHTD, which leaves the company with a cash runway through to the first half of 2016, taking us to data on this first trial.”

The preparation and regulatory filings are expected to be completed in the second half of 2015, with initiation of a Phase 1A study early in the first quarter of 2016.

iCo has also been building its intellectual property position around the Oral Amphotericin B asset. The company was issued composition of matter and use patents, titled:   Formulations for Oral Administration of Therapeutic Agents and Related Methods, issued in the United States, Russia, Singapore, New Zealand and notice of allowance in China. Management is aggressively pursuing further patent issuances in multiple jurisdictions as it moves towards the clinic.

Current Amphotericin B product, AmBisome, marketed by Gilead, had sales of $352 million in 2013, but it is severely limited in its application because of its toxicity and IV delivery. An oral delivery platform would open up the market for the treatment of infections and outpatient treatment regimes, as well as developing world treatments where IV is not practical.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company has exclusive worldwide rights to iCo-007 and iCo-008, as well as an oral drug delivery platform. The first platform candidate being tested is the Oral Amp B Delivery system, utilizing a known anti-fungal drug to treat latent HIV reservoirs, parasitic and life-threatening infectious diseases. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws. Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>
214 iCo Therapeutics Announces Second Quarter 2014 Financial Results August 29, 2014, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the six months ended June 30, 2014. Amounts, unless specified otherwise, are expressed in Canadian dollars and http://icotherapeutics.com/newsroom/index.php?content_id=214 2014-08-29 04:00:00 August 29, 2014, Vancouver, Canada — iCo Therapeutics (“iCo” or “the Company”) (TSX-V: ICO) (OTCQX: ICOTF), today reported financial results for the six months ended June 30, 2014. Amounts, unless specified otherwise, are expressed in Canadian dollars and presented under International Financial Reporting Standards (“IFRS”).

Second Quarter 2014 Highlights

  • Announced top-line results related to the eight month visual acuity (VA) primary endpoint for subjects enrolled in the Phase 2 iDEAL Study evaluating the efficacy and safety of iCo-007 after repeated injections in patients with DME.  Further data analysis at twelve months including secondary endpoints and sub-group patient populations will be announced in the next two months.
  • Poster presentation by research collaborators at the Association of Research and Ophthalmology (ARVO) 2014 Annual Meeting titled "Demographics and Baseline Characteristics of the iDEAL Study: A Randomized, Multi-center, Phase II Study of the safety, Tolerability, and Bioactivity of Repeated Intravitreal Injections of iCO-007 as Monotherapy or in Combination with Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema with Involvement of the FoveAL Center".

Subsequent Events to Quarter End

  • Announced that all nominees listed in the management information circular dated May 28, 2014 were elected as directors of the Company at the 2014 Annual Meeting of Shareholders, held on Friday, June 27, 2014.
  • Reported results of its Oral Amphotericin B (Oral Amp B) drug candidate targeting latent HIV reservoirs The study, conducted by ImmuneCarta®, the immune monitoring business unit of Caprion, evaluated in vitro effectiveness of Oral Amp B in reactivating latent HIV viral reservoirs which remain present in individuals despite intensive treatment with antiretroviral therapy.

Summary Second Quarter 2014 Results
iCo incurred total comprehensive loss of $1,617,040 (loss per share of $0.02) for the six months ended June 30, 2014 compared to a total comprehensive loss of $2,886,831 (loss per share of $0.05) for the six months ended June 30, 2013, representing a decrease of $1,269,791 in comprehensive loss. The decrease in net comprehensive loss is primarily a result of a $259,755 increase in the carrying value of our investment in Immune Pharmaceuticals, as well as a decrease in expenses associated with the iDEAL trial.

Research and development expenses were $1,026,287 for the six months ended June 30, 2014 compared to $2,189,830 for the six months ended June 30, 2013, representing a reduction of $1,163,543. This decrease in research and development expenses is based mainly on reduced expenses associated with the iDEAL study.

For the six months ended June 30, 2014 general and administrative expenses were $935,374 compared to $1,166,480 for the six months ending June 30, 2013, representing a decrease of $231,106, primarily as a result of reduced stock based compensation expense and professional fees.

Liquidity and Outstanding Share Capital
As at June 30, 2014, we had cash and cash equivalents and short-term investments of $6,480,200.

As at August 29, 2014, we had an unlimited number of authorized common shares with 84,457,713 common shares issued and outstanding.

For complete financial results, please see our filings at www.sedar.com.

About iCo Therapeutics
iCo Therapeutics in-licenses and redefines existing drug candidates or generics by employing reformulation and delivery technologies for new or expanded use indications. The Company has exclusive worldwide rights to two drug candidates - iCo-007 for Diabetic Macular Edema (DME) and iCo-008 for other sight-threatening diseases. iCo-007 is in Phase 2 clinical studies for DME. With Phase 2 clinical history, iCo-008 is targeted for the treatment of keratoconjunctivitis and wet age-related macular degeneration. In addition, iCo holds worldwide rights to an oral drug delivery platform. The first platform candidate is the Oral Amp B Delivery system, utilizing a known anti-fungal drug to treat life-threatening infectious diseases. iCo trades on the TSX Venture Exchange under the symbol "ICO" and the OTCQX under the symbol “ICOTF”. For more information, visit the Company website at: www.icotherapeutics.com.

No regulatory authority has approved or disapproved the content of this press release. Neither the TSX Venture Exchange nor its Regulatory Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this press release.

Forward Looking Statements
Certain statements included in this press release may be considered forward-looking statements” within the meaning of applicable securities laws. Forward-looking statements can be identified by words such as: “anticipate,” “intend,” “plan,” “goal,” “seek,” “believe,” “project,” “estimate,” “expect,” “strategy,” “future,” “likely,” “may,” “should,” “will,” and similar references to future periods and includes, but is not limited to, statements about the intended use of proceeds of the Offering. Such statements involve known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by such statements, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on iCo's current beliefs as well as assumptions made by and information currently available to iCo and relate to, among other things, anticipated financial performance, business prospects, strategies, regulatory developments, market acceptance and future commitments. Readers are cautioned not to place undue reliance on these forward-looking statements, which are based only on information currently available to iCo and speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by iCo in its public securities filings and on its website, actual events may differ materially from current expectations. iCo disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.

Mr. John Meekison, CFO
iCo Therapeutics
604-602-9414 x 224
meekison@icotherapeutics.com

Michael Moore, Investor Relations
TMX Equicom
858-886-7813
mmoore@tmxequicom.com

]]>